CERI Research Focus Areas Women's Health
07

Women's
Health
Research

Women's Health

Advancing understanding of conditions affecting women across the life course — including infectious diseases, reproductive health, and microbiome-related conditions — with interventions and diagnostics tailored to African contexts.

Reproductive Health
HIV & STIs
Maternal Health
Microbiome
Gender-Responsive
Women's Health Across the Life Course
Research Active
Adolescent
Reproductive Age
Maternal
Older Women
HIV & STI Research
93%
Reproductive Health
87%
Vaginal Microbiome
79%
Maternal & Child Health
82%
20K+
Women Enrolled
10+
African Countries
120+
Publications
// Research Focus

What the Team
Investigates

FOCUS · 01
HIV & STIs in Women

Investigating biological, behavioural, and social drivers of HIV and STI acquisition in women, and evaluating prevention strategies including PrEP, vaccines, and microbiocides.

HIV Prevention PrEP STIs
FOCUS · 02
Maternal & Perinatal Health

Studying infectious disease during pregnancy, vertical transmission, preterm birth, and neonatal outcomes to improve maternal and child health across Africa.

Vertical Transmission Preterm Birth Neonatal
FOCUS · 03
Vaginal Microbiome

Characterising vaginal microbiome composition and its role in HIV susceptibility, STI risk, reproductive outcomes, and overall gynaecological health.

Lactobacillus Dysbiosis HIV Risk
FOCUS · 04
Diagnostics for Women

Developing and validating point-of-care diagnostics for reproductive tract infections, cervical disease, and other conditions disproportionately affecting women.

Point-of-Care Cervical Health Validation
FOCUS · 05
Interventions & Therapeutics

Evaluating gender-responsive interventions including vaccines, topical therapies, and microbiome-modulating treatments tailored to African women's health needs.

Vaccines Topical PrEP Therapeutics
FOCUS · 06
Gender-Responsive Research

Addressing structural gaps in women-centred health research by integrating gender analysis, community engagement, and equity-focused approaches into all studies.

Gender Equity Community Policy
// Research Workflow

From Community
to Clinical Impact

STEP · 01
Community Engagement

Building trust and partnerships with communities to support participant recruitment, ethical research conduct, and community-informed study design.

STEP · 02
Sample & Data Collection

Collecting clinical samples, microbiome specimens, and behavioural data from cohorts of women across diverse African settings.

STEP · 03
Laboratory Analysis

Immunological, genomic, and microbiome profiling to characterise disease mechanisms and identify biomarkers and targets for intervention.

STEP · 04
Integrated Analysis

Combining biological, clinical, and social data to understand multifactorial drivers of women's health outcomes across the life course.

STEP · 05
Clinical Translation

Translating findings into diagnostics, prevention tools, treatment guidelines, and gender-responsive public health policies.

// Research Themes

Key Areas of
Investigation

HIV Prevention in Women PrEP, Vaccines & Microbiocides
Evaluating oral and injectable PrEP uptake, vaccine-induced immunity, and topical microbiocide efficacy in African women at high HIV risk.
Active
Vaginal Microbiome & HIV Risk Dysbiosis, Inflammation & Susceptibility
Understanding how vaginal microbiome composition modulates HIV acquisition risk and local immune activation in African women.
Active
Pregnancy & Infectious Disease Vertical Transmission & Neonatal Outcomes
Investigating HIV, CMV, syphilis, and other infections during pregnancy and their impact on maternal, perinatal, and neonatal health outcomes.
Active
Cervical Health HPV, Cervical Cancer & Screening
Studying HPV prevalence, cervical dysplasia, and cancer risk in African women, and evaluating point-of-care screening and treatment approaches.
Active
Women's Health Across the Life Course Adolescent to Older Women
Addressing health needs at each life stage — from adolescent sexual health to menopause-related conditions — with context-specific African interventions.
Emerging
// Working With

Research &
Partner Network

Microbiome Unit

Joint research on vaginal microbiome composition, dysbiosis, and its role in HIV risk and reproductive health outcomes.

Immunology Unit

Characterising local and systemic immune responses in women to inform vaccine design and prevention strategies.

Clinical Partners

Collaborating with maternal health clinics, antenatal care networks, and gynaecology services to recruit participants and translate findings.

IAVI / HVTN / WHO

Contributing to international vaccine and prevention trials through shared immunological and microbiome data from African women.

// The People

Meet the
Team

Prof Jo-Ann Passmore
Prof Jo-Ann Passmore

Professor of Medical Virology and Microbiome Research

// Research Output

Latest
Publications

2026
‘The not talking is actually what kills you’– young South African women’s communication barriers about sexual health

Hartley F, Trappler J, Gill K, Bekker L, MacKenny V, Knight L,…

Culture, Health & Sexuality 1-12