CERI Research Focus Areas Population Health & Modelling
05

Population Health
& Modelling

SACEMA sacema.org

Using mathematical and statistical models to understand disease transmission, evaluate interventions, and guide public health strategy in Africa — spanning HIV, TB, emerging infections, and non-communicable diseases.

Epidemiological Modelling
Disease Transmission
Intervention Evaluation
HIV & TB
Capacity Building
Modelling Output Dashboard
Models Running
Epidemic Forecasting
Transmission Models
Intervention Analysis
Scenario Planning
Spatial Modelling
Geographic Spread
Population Dynamics
Age-Structured Models
HIV Transmission Model
92%
TB Burden Forecasting
85%
Outbreak Intervention
78%
30+
Models Developed
20+
African Countries
200+
Publications
// Research Focus

What the Team
Investigates

FOCUS · 01
Epidemic Modelling

Developing mathematical models of disease transmission to forecast epidemic trajectories, estimate burden, and evaluate the impact of public health interventions.

SIR/SEIR Compartmental Agent-Based
FOCUS · 02
Intervention Evaluation

Using modelling to assess the effectiveness, cost-efficiency, and population-level impact of treatment, vaccination, and prevention programmes.

Scenario Analysis Cost-Effectiveness Policy
FOCUS · 03
Genomic Epidemiology

Integrating genomic sequence data with epidemiological models to reconstruct transmission chains and understand pathogen spread at population level.

Phylodynamics Transmission WGS Integration
FOCUS · 04
Spatial & Social Modelling

Incorporating geographic, demographic, and social determinants into models to capture heterogeneity in disease burden and intervention response.

GIS Social Networks Demographics
FOCUS · 05
NCDs & Multi-Morbidity

Modelling the intersection of infectious diseases and non-communicable diseases in African populations, particularly HIV/TB co-morbidity and metabolic conditions.

HIV/TB Diabetes Co-morbidity
FOCUS · 06
Capacity Building

Training the next generation of African epidemiological modellers through workshops, short courses, fellowships, and postgraduate supervision.

Training Fellowships Africa-Led
// Modelling Workflow

From Data
to Policy

STEP · 01
Data Integration

Integrating genomic, epidemiological, clinical, and social data from surveillance systems, cohorts, and partner health facilities.

STEP · 02
Model Development

Building mathematical and statistical models calibrated to local epidemiological context using Bayesian and frequentist frameworks.

STEP · 03
Calibration & Validation

Fitting models to observed data and validating against independent datasets to ensure reliability and generalisability.

STEP · 04
Scenario Analysis

Running intervention scenarios to project future disease burden and compare the impact of different public health strategies.

STEP · 05
Policy Translation

Communicating findings to health ministries, funders, and WHO to inform resource allocation, programme design, and epidemic response.

// Disease Areas

Diseases &
Health Priorities

HIV / AIDS Transmission Dynamics & Treatment Impact
Modelling HIV transmission networks, evaluating ART scale-up, PrEP programmes, and assessing progress toward epidemic control targets.
Active
Tuberculosis Burden Estimation & Control Strategies
Forecasting TB burden, evaluating preventive therapy programmes, and modelling HIV-TB co-infection dynamics across sub-Saharan Africa.
Active
Emerging Infections Outbreak Forecasting & Response
Rapid model deployment during outbreaks of SARS-CoV-2, Mpox, Ebola, and other emerging pathogens to support real-time epidemic response.
Active
Non-Communicable Diseases Burden & Risk Factor Modelling
Modelling the growing burden of hypertension, diabetes, and cardiovascular disease in African populations, including interactions with infectious diseases.
Emerging
Vaccine Impact Coverage Optimisation & Equity
Modelling optimal vaccine rollout strategies, coverage targets, and equity considerations to maximise population-level protection in African settings.
Active
// Working With

Research &
Partner Network

Genomics Unit

Integrating whole-genome sequencing data into phylodynamic models to reconstruct transmission chains and outbreak origins.

Data Science Unit

Collaborating on data pipelines, dashboards, and analytical tools that feed epidemiological models with real-time surveillance data.

WHO / Africa CDC

Providing modelling support to continental health bodies for epidemic preparedness, burden estimation, and intervention planning.

Health Ministries

Translating modelling outputs into actionable policy recommendations for national HIV, TB, and epidemic response programmes.

// The People

Meet the
Team

// Research Output

Latest
Publications

No publications found.