TEAM
Prof Frank Tanser
CERI Team

Prof Frank
Tanser

Director: SACEMA

 

Professor Frank Tanser is a South African scientist whose research aims to evaluate and design intervention strategies to drive back the HIV epidemic and its negative consequences in communities hardest hit by the epidemic. His pivotal work over the past 25 years has provided substantial insights into the evolving and dynamic nature of the HIV epidemic and its key drivers, informing HIV prevention and treatment efforts in sub-Saharan Africa.

His research into the population-level impacts of the antiretroviral therapy (ART) roll-out has led to wide-reaching and rapid changes to government policy on how ART programmes in South Africa are designed and implemented. In particular, a seminal study he published in one of the world’s leading scientific journals – Science – was the first to show that nurse-led and decentralised HIV programmes in rural areas could be successful in reducing HIV transmission at the population-level.

Frank holds masters degrees from Imperial College London and Rhodes University and a doctorate from UKZN. He is a faculty member at AHRI and professor of global health at Stellenbosch University. He has served as a consultant and advisor to several high-profile organisations including the Mailman School of Public Health, USAID, the Futures Group International and UNAIDS. He currently serves on the board of The Lancet HIV and was member of the international scientific and technical advisory committee to the executive director of UNAIDS.

Frank has published over 250 papers in high-ranking international journals and his research has been cited over 33 000 times. He has been the recipient of numerous scientific grants and has raised over $85-million in external research funding to date. He is the founding director of the Lincoln International Institute for Rural Health – an international institute set up to study the health of rural populations across the globe. He was also a founder member of the Africa Centre for Population Health in 1998, and was responsible for building Africa’s first comprehensive population-based GIS system at the centre. In 2017 Frank was honoured by the South African Medical Research Council with the gold medal scientific achievement award in recognition of the excellence of his research. The award recognises outstanding scientists who have undertaken seminal research that has impacted directly on the health of populations in developing countries. In 2019, The Royal Geographical Society awarded him the Back Award for “conducting applied research that has made an outstanding contribution to the development of national or international public policy”.

Linkedin

// Research Output

Publications

2026
Peer network approaches for improving HIV testing, prevention and care utilisation among men in sub-Saharan Africa: a scoping review

Otambo W, Harling G, Inghels M, Otto M, Blose N, Tram K, Tanser F, Mee P

BMJ Open
16:e106124
2026
Do men face greater barriers to accessing HIV testing services than women? Might HIV self-testing be the answer? Evidence from a longitudinal survey in east Zimbabwe (2018–2023)

Otambo W, Mandizvidza P, Moorhouse L, Inghels M, Moyo R, Okango E, Tsenesa B, Maswera R, Dzamatira F, Gregson S, Tanser F, Nyamukapa C, Mee P

PLOS Global Public Health
6:e0006125
2024
Associations of inter-annual rainfall decreases with subsequent HIV outcomes for persons with HIV on antiretroviral therapy in Southern Africa: a collaborative analysis of cohort studies

Trickey A, Johnson LF, Fung F, Bonifacio R, Iwuji C, Biraro S, Bosomprah S, Chirimuta L, Euvrard J, Fatti G, Fox MP, Von Groote P, Gumulira J, Howard G, Jennings L, Kiragga A, Muula G, Tanser F, Wagener T, Low A, Vickerman P

BMC Infect Dis
doi: 10.1186/s12879-023-08902-9
2024
Convergence of HIV and non-communicable disease epidemics: geospatial mapping of the unmet health needs in an HIV hyperendemic community in South Africa

Cuadros DF, Devi C, Singh U, Olivier S, Castle AC, Moosa Y, Edwards JA, Kim HY, Siedner MJ, Wong EB, Tanser F

BMJ Glob Health
9(1):e012730. doi: 10.1136/bmjgh-2023-012730
2024
Effect of a male-targeted digital decision support application aimed at increasing linkage to HIV care among men: Findings from the HITS cluster randomized clinical trial in rural South Africa

Kim HY, Inghels M, Mathenjwa T, Shahmanesh M, Seeley J, Matthews P, Wyke S, McGrath N, Adeagbo O, Gareta D, Yapa HM, Zuma T, Dobra A, Blandford A, Bärnighausen T, Tanser F

medRxiv [Preprint]
2024.03.15.24304373. doi: 10.1101/2024.03.15.24304373
2024
The impact of a conditional financial incentive on linkage to HIV care: Findings from the HITS cluster randomized clinical trial in rural South Africa

Kim HY, Inghels M, Mathenjwa T, Shahmanesh M, Seeley J, Matthews P, McGrath N, Adeagbo O, Gareta D, Yapa HM, Zuma T, Dobra A, Bärnighausen T, Tanser F

medRxiv [Preprint]
2024.03.15.24304278. doi: 10.1101/2024.03.15.24304278
2024
HIV transmission dynamics and population-wide drug resistance in rural South Africa

Kemp SA, Kamelian K, Cuadros DF; PANGEA Consortium; Vukuzazi Team; Cheng MTK, Okango E, Hanekom W, Ndung'u T, Pillay D, Bonsall D, Wong EB, Tanser F, Siedner MJ, Gupta RK

Nat Commun.
15(1):3644. doi: 10.1038/s41467-024-47254-z
2024
Population impacts of conditional financial incentives and a male-targeted digital decision support application on the HIV treatment cascade in rural KwaZulu Natal: findings from the HITS cluster randomized clinical trial

Inghels M, Kim HY, Mathenjwa T, Shahmanesh M, Seeley J, Wyke S, Matthews P, Adeagbo O, Gareta D, McGrath N, Yapa HM, Blandford A, Zuma T, Dobra A, Bärnighausen T, Tanser F

J Int AIDS Soc.
27(5):e26248. doi: 10.1002/jia2.26248
2024
Geospatial and temporal mapping of detectable HIV-1 viral loads amid dolutegravir rollout in KwaZulu-Natal, South Africa. PLOS Glob Public Health

Gounder L, Tomita A, Lessells R, Moodley S, Francois KL, Khan A, Pillay M, Manyana SC, Govender S, Govender K, Moodley P, Parboosing R, Msomi N, Tanser F, Naidoo K, Chimukangara B

PLOS Glob Public Health
4(5):e0003224. doi: 10.1371/journal.pgph.0003224
2023
High prevalence of self-reported sexually transmitted diseases among older adults in Tanzania: results from the list experiment

Kim HY, Rohr J, Leyna GH, Killewo J, Tomita A, Tanser F, Bärnighausen T

Ann Epidemiol.
S1047-2797(23)00086-8. doi: 10.1016/j.annepidem.2023.05.001
2023
International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa. Abacavir safety and effectiveness in young infants with HIV in South African observational cohorts

de Waal R, Rabie H, Technau KG, Eley B, Sipambo N, Cotton M, Boulle A, Wood R, Tanser F, Fatti G, Egger M, Davies MA

Antivir Ther.
28(2):13596535231168480. doi: 10.1177/13596535231168480
2023
Convergence of HIV and non-communicable disease epidemics: Geospatial mapping of the unmet health needs in a HIV Hyperendemic South African community.

Cuadros DF, Devi C, Singh U, Olivier S, Castle A, Moosa Y, Edwards JA, Kim HY, Siedner MJ, Wong EB, Tanser F

medRxiv
2023.03.27.23287807. doi: 10.1101/2023.03.27.23287807
2023
Spatial variations in STIs among women enrolled in HIV prevention clinical trials in Durban, KwaZulu-Natal

Dassaye R, Wand H, Reddy T, Tanser F, Sartorius B, Morris N, Ramjee G

SAHARA J.
(1):2193238. doi: 10.1080/17290376.2023.2193238
2022
The geography and inter-community configuration of new sexual partnership formation in a rural South African population over fourteen years (2003–2016)

Kim H-Y, Cuadros D, Wilkinson E, Junqueira DM, de Oliveira T, Tanser F

PLoS Global Public Health
https://doi.org/10.1371/journal.pgph.0000055
2022
The role of high-risk geographies in the perpetuation of the HIV epidemic in rural South Africa: A spatial molecular epidemiology study

Cuadros DF, de Oliveira T, Graf T, Junqueira DM, Wilkinson E, Lemey P, Barnighausen T, Kim H-Y, Tanser F

PLoS Global Public Health
https://doi.org/10.1371/journal.pgph.0000105
2021
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa

Wilkinson E, Giovanetti M, Tegally H, San JE, Lessells R, Cuadros D, Martin DP, Rasmussen DA, Zekri AN, Sangare AK, Ouedraogo AS, Sesay AK, Priscilla A, Kemi AS, Olubusuyi AM, Oluwapelumi AOO, Hammami A, Amuri AA, Sayed A, Ouma AEO, Elargoubi A, Ajayi NA, Victoria AF, Kazeem A, George A, Trotter AJ, Yahaya AA, Keita AK, Diallo A, Kone A, Souissi A, Chtourou A, Gutierrez AV, Page AJ, Vinze A, Iranzadeh A, Lambisia A, Ismail A, Rosemary A, Sylverken A, Femi A, Ibrahimi A, Marycelin B, Oderinde BS, Bolajoko B, Dhaala B, Herring BL, Njanpop-Lafourcade BM, Kleinhans B, McInnis B, Tegomoh B, Brook C, Pratt CB, Scheepers C, Akoua-Koffi CG, Agoti CN, Peyrefitte C, Daubenberger C, Morang'a CM, Nokes DJ, Amoako DG, Bugembe DL, Park D, Baker D, Doolabh D, Ssemwanga D, Tshiabuila D, Bassirou D, Amuzu DSY, Goedhals D, Omuoyo DO, Maruapula D, Foster-Nyarko E, Lusamaki EK, Simulundu E, Ong'era EM, Ngabana EN, Shumba E, El Fahime E, Lokilo E, Mukantwari E, Philomena E, Belarbi E, Simon-Loriere E, Anoh EA, Leendertz F, Ajili F, Enoch FO, Wasfi F, Abdelmoula F, Mosha FS, Takawira FT, Derrar F, Bouzid F, Onikepe F, Adeola F, Muyembe FM, Tanser F, Dratibi FA, Mbunsu GK, Thilliez G, Kay GL, Githinji G, van Zyl G, Awandare GA, Schubert G, Maphalala GP, Ranaivoson HC, Lemriss H, Anise H, Abe H, Karray HH, Nansumba H, Elgahzaly HA, Gumbo H, Smeti I, Ayed IB, Odia I, Ben Boubaker IB, Gaaloul I, Gazy I, Mudau I, Ssewanyana I, Konstantinus I, Lekana-Douk JB, Makangara JC, Tamfum JM, Heraud JM, Shaffer JG, Giandhari J, Li J, Yasuda J, Mends JQ, Kiconco J, Morobe JM, Gyapong JO, Okolie JC, Kayiwa JT, Edwards JA, Gyamfi J, Farah J, Nakaseegu J, Ngoi JM, Namulondo J, Andeko JC, Lutwama JJ, O'Grady J, Siddle K, Adeyemi KT, Tumedi KA, Said KM, Hae-Young K, Duedu KO, Belyamani L, Fki-Berrajah L, Singh L, Martins LO, Tyers L, Ramuth M, Mastouri M, Aouni M, El Hefnawi M, Matsheka MI, Kebabonye M, Diop M, Turki M, Paye M, Nyaga MM, Mareka M, Damaris MM, Mburu MW, Mpina M, Nwando M, Owusu M, Wiley MR, Youtchou MT, Ayekaba MO, Abouelhoda M, Seadawy MG, Khalifa MK, Sekhele M, Ouadghiri M, Diagne MM, Mwenda M, Allam M, Phan MVT, Abid N, Touil N, Rujeni N, Kharrat N, Ismael N, Dia N, Mabunda N, Hsiao NY, Silochi NB, Nsenga N, Gumede N, Mulder N, Ndodo N, Razanajatovo NH, Iguosadolo N, Judith O, Kingsley OC, Sylvanus O, Peter O, Femi O, Idowu O, Testimony O, Chukwuma OE, Ogah OE, Onwuamah CK, Cyril O, Faye O, Tomori O, Ondoa P, Combe P, Semanda P, Oluniyi PE, Arnaldo P, Quashie PK, Dussart P, Bester PA, Mbala PK, Ayivor-Djanie R, Njouom R, Phillips RO, Gorman R, Kingsley RA, Carr RAA, El Kabbaj S, Gargouri S, Masmoudi S, Sankhe S, Lawal SB, Kassim S, Trabelsi S, Metha S, Kammoun S, Lemriss S, Agwa SHA, Calvignac-Spencer S, Schaffner SF, Doumbia S, Mandanda SM, Aryeetey S, Ahmed SS, Elhamoumi S, Andriamandimby S, Tope S, Lekana-Douki S, Prosolek S, Ouangraoua S, Mundeke SA, Rudder S, Panji S, Pillay S, Engelbrecht S, Nabadda S, Behillil S, Budiaki SL, van der Werf S, Mashe T, Aanniz T, Mohale T, Le-Viet T, Schindler T, Anyaneji UJ, Chinedu U, Ramphal U, Jessica U, George U, Fonseca V, Enouf V, Gorova V, Roshdy WH, Ampofo WK, Preiser W, Choga WT, Bediako Y, Naidoo Y, Butera Y, de Laurent ZR, Sall AA, Rebai A, von Gottberg A, Kouriba B, Williamson C, Bridges DJ, Chikwe I, Bhiman JN, Mine M, Cotten M, Moyo S, Gaseitsiwe S, Saasa N, Sabeti PC, Kaleebu P, Tebeje YK, Tessema SK, Happi C, Nkengasong J, de Oliveira T

Science
DOI: 10.1126/science.abj4336
2020
Opportunities and Challenges in HIV Treatment as Prevention Research: Results from the ANRS 12249 Cluster-Randomized Trial and Associated Population Cohort

Tanser F, Kim H-Y, Vandormael A, Iwuji C, Barnighausen T

Current HIV/AIDS Reports
17:97–108 https://doi.org/10.1007/s11904-020-00487-1
2020
Spatial clustering of food insecurity and its association with depression: a geospatial analysis of nationally representative South African data, 2008–2015

Tomita A, Cuadros DF, Mabhaudhi T, Sartorius B, Ncama BP, Dangour AD, Tanser F, Modi AT, Slotow R, Burns JK

Scientific Reports
(2020) 10:13771. https://doi.org/10.1038/s41598-020-70647-1
2020
HIV incidence declines in a rural South African population: a G-imputation approach for inference

Vandormael A, Cuadros D, Dobra A, Barnighausen T, Tanser F

BMC Public Health
20:1205 https://doi.org/10.1186/s12889-020-09193-4
2020
Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa

Mogeni P, Vandormael A, Cuadros D, Appleton C, Tanser F

Elife
9. pii: e54012. doi: 10.7554/eLife.54012
2020
The state of the HIV epidemic in rural KwaZulu-Natal, South Africa: a novel application of disease metrics to assess trajectories and highlight areas for intervention

Vandormael A, Cuadros D, Kim HY, Bärnighausen T, Tanser F

Int J Epidemiol.
pii: dyz269. doi: 10.1093/ije/dyz269
2020
HIV seroconcordance among heterosexual couples in rural KwaZulu-Natal, South Africa: a population-based analysis

Kim HY, Harling G, Vandormael A, Tomita A, Cuadros DF, Bärnighausen T, Tanser F

J Int AIDS Soc.
23(1):e25432. doi: 10.1002/jia2.25432
2019
Declines in HIV incidence among men and women in a South African population-based cohort

Vandormael A, Akullian A, Siedner M, de Oliveira T, Bärnighausen T, Tanser F

Nature Communications
10(1):5482. doi: 10.1038/s41467-019-13473-y
2019
Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: a systematic review and meta-analysis

Birdthistle I, Tanton C, Tomita A, de Graaf K, Schaffnit SB, Tanser F, Slaymaker E

Lancet Global Health
7: e1521–40
2019
Space-time clustering of recently diagnosed tuberculosis and impact of ART scale-up: Evidence from an HIV hyper-endemic rural South African population

Tomita A, Smith CM, Lessells RJ, Pym A, Grant AD, de Oliveira T, Tanser F

Scientific Reports
https://doi.org/10.1038/s41598-019-46455-7
2019
Effect of ART scale-up and female migration intensity on risk of HIV acquisition: results from a population-based cohort in KwaZulu-Natal, South Africa

Dzomba A, Tomita A, Vandormael A, Govender K, Tanser F

BMC Public Health
19(1):196:doi: 10.1186/s12889-019-6494-x
2019
Estimating trends in the incidence rate with interval censored data and time-dependent covariates

Vandormael A, Tanser F, Cuadros D, Dobra A

Stat Methods Med Res
962280219829892. doi: 10.1177/0962280219829892
2019
Sociobehavioral and community predictors of unsuppressed HIV viral load: multilevel results from a hyperendemic rural South African population

Tomita A, Vandormael A, Bärnighausen T, Phillips A, Pillay D, De Oliveira T, Tanser F

AIDS
33(3):559–569
2019
Spatial structure of depression in South Africa: A longitudinal panel survey of a nationally representative sample of households

Cuadros DF, Tomita A, Vandormael A, Slotow R, Burns JK, Tanser F

Scientific Reports
9(1):979:doi.org/10.1038/s41598-018-37791-1
2018
Tracking external introductions of HIV using phylodynamics reveals a major source of infections in rural KwaZulu-Natal, South Africa

Rasmussen DA, Wilkinson E, Vandormael A, Tanser F, Pillay D, Stadler T, de Oliveira T

Virus Evolution
4(2): vey037
2018
Spatial clustering of drug-resistant tuberculosis in Hlabisa subdistrict, KwaZulu-Natal, 2011-2015

Smith CM, Lessells R, Grant AD, Herbst K, Tanser F

Int J Tuberc Lung Dis.
1;22(3):287-293. doi: 10.5588/ijtld.17.0457
2018
Impact of the scale-up of piped water on urogenital schistosomiasis infection in rural South Africa

Tanser F, Azongo DK, Vandormael A, Barnighausen T, Appleton C

eLIFE
7:e33065
2018
Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial

Iwuji CC, Orne-Gliemann J, Larmarange J, Balestre E, Thiebaut R, Tanser F, Okesola N, Makowa T, Dreyer J, Herbst K, McGrath N, Barnighausen T, Boyer S, de Oliveira T, Rekacewicz C, Bazin B, Newell ML, Pillay D, Dabis F, for the ANRS 12249 TasP Study Group

Lancet HIV
http://dx.doi.org/10.1016/S2352-3018(17)30205-9
2018
High percentage of undiagnosed HIV cases within a hyperendemic South African community: a population-based study

Vandormael A, de Oliveira T, Tanser F, Barnighausen T, Herbeck JT

J Epidemiol Community Health
doi: 10.1136/jech-2017-209713
2017
Green environment and incident depression in South Africa: a geospatial analysis and mental health implications in a resource-limited setting

Tomita A, Vandormael AM, Cuadros D, Di Minin E, Heikinheimo V, Tanser F, Slotow R, Burns JK

Lancet Planetary Health
1:152?62
2017
Effect of population viral load on prospective HIV incidence in a hyperendemic rural African community

Tanser F, Vandormael A, Cuadros D, Phillips AN, de Oliveira T, Tomita A, Barnighausen T, Pillay D

Science Translational Medicine
9:eaam8012
2017
Longitudinal trends in the prevalence of detectable HIV viremia: Population-based evidence from rural KwaZulu-Natal, South Africa

Vandormael A, Barnighausen T, Herbeck J, Tomita A, Phillips A, Pillay D, de Oliveira T, Tanser F

Clin Infect Dis.
doi: 10.1093/cid/cix976
2017
Sexual partnership age pairings and risk of HIV acquisition in rural South Africa

Akulliana A, Bershteyna A, Kleina D, Vandormael A, Barnighausen T, Tanser F

AIDS
DOI:10.1097/QAD.0000000000001553
2017
Incidence rate estimation, periodic testing and the limitations of the mid-point imputation approach

Vandormael A, Dobra A, Barnighausen T, de Oliveira T, Tanser F

International Journal of Epidemiology
doi.org/10.1093/ije/dyx134
2017
Social disequilibrium and the risk of HIV acquisition: A multilevel study in rural KwaZulu-Natal Province, South Africa

Tomita A, Vandormael AM, Barnighausen T, de Oliveira T, Tanser F

J Acquir Immune Defic Syndr.
10.1097/QAI.0000000000001349
2016
Genome-Wide Association Study of HIV Whole Genome Sequences Validated using Drug Resistance

Power RA, Davaniah S, Derache A, Wilkinson E, Tanser F, Gupta RK, Pillay D, de Oliveira T

PLoS One
11(9):e0163746
2016
Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana

Moyo S, Vandormael A, Wilkinson E, Engelbrecht S, Gaseitsiwe S, Kotokwe, KP, Musonda R, Tanser F, Essex M, Novitsky V, de Oliveira T

PLoS One
11(8):DOI:10.1371/journal.pone.0160649
2016
Increasing HIV-1 drug resistance between 2010 and 2012 in adults participating in population-based HIV surveillance in rural KwaZulu-Natal South Africa

Manasa J, Danaviah S, Lessells RJ, Elshareef M, Tanser F, Wilkinson E, Pillay S, Mthiyane H, Mwambi H, Pillay D, de Oliveira T

AIDS Res Hum Retroviruses
32(8):763-769
2016
Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART

Vandormael AM, Boulware DR, Tanser FC, Barnighuasen TW, Stott KE, de Oliveira T

J Acquir Immune Defic Syndr.
71(4):462?466
2014
Concentrated HIV subepidemics in generalized epidemic settings

Tanser F, de Oliveira T, Maheu-Giroux M, Barnighausen T

Curr Opin HIV AIDS
9(2):115-125
2013
High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa

Tanser F, Barnighausen T, Grapsa E, Zaidi J, Newell M-L.

Science
339(6122):966-971
2010
The TB challenge in a rural South African HIV programme

Houlihan C, Mutevedzi P, Lessells R, Cooke G, Tanser F, Newell ML

BMC Infect Dis
10:23