TEAM
Dr Marije Hofstra
CERI Team

Dr Marije
Hofstra

Post-Doctoral Fellow
// Affiliations
Primary
CERI - Stellenbosch University
// Education
Specialization Medical Microbiology
UMC Utrecht, 2020
PhD in Medicine
University of Utrecht, 2019
Global Clinical Scholars Research Training Program
Harvard Medical School, 2017
Medical Doctor (MD)
University of Utrecht, 2012

Marije Hofstra, M.D./Ph.D., is a clinical microbiologist with a passion for global health. She has received her medical and specialization training in the Netherlands. She has led studies on HIV drug resistance in different settings in Europe, the Caribbean and South Africa. Her research at CERI is primarily centred on translating innovation in laboratory diagnostics and bioinformatics in ways that directly benefit individual patients and public health. She is working on metagenomic next-generation sequencing for diagnosis of infections, genomic surveillance, pathogen discovery and host response investigations. She is also interested in leveraging machine learning based approaches to aid in fast interpretation and translation into actionable results.

// Research Output

Publications

2025
Identifying genomic surveillance gaps in Africa for the global public health response to West Nile virus: a systematic review

Moir M, Sitharam N, Hofstra L, Dor G, Mwanyika G, Ramphal Y, Reichmuth M, San J, Gifford R, Wilkinson E, Tshiabuila D, Preiser W, Konou A, Bitew M, Onoja A, Paganotti G, Abera A, Maror J, Kayiwa J, Abuelmaali S, Lusamaki E, de Oliveira T, Alcantara L, Holmes E, Padane A, Musa A, Abera A, Campbell A, Ssemaganda A, Ahouidi A, Muianga A, Samson A, Onoja A, Alemu B, Foka C, Baxter C, van Zyl D, de Castro Silva D, Martin D, Wilkinson E, Kouma E, Simo F, Mwanyika G, Godebo G, D’or G, Tegally H, Omara I, Maror J, Poonagavan J, Juma J, Oludele J, Xavier J, Lourenco J, Fokam J, Maeka K, Singh L, Chabuka L, Issaka M, Hofstra M, Giovanetti M, Faye M, Koffi M, Owusu M, Dikongo M, Alimohamed M, Bitew M, Moir M, Kraemer M, Sitharam N, Jerome N, Mbhele N, Miantsatian Andry N, Tomori O, Magalutcheemee R, Guimaraes R, Oyola S, Abuelmaali S, Golubchik T, Fonseca V, Preiser W, Ramphal Y, Venter M, Burt F, Baxter C, Lessells R, de Oliveira T, Tegally H

The Lancet Microbe
6:101176
2025
Identifying genomic surveillance gaps in Africa for the global public health response to West Nile Virus

Moir M, Sitharam N, Hofstra M, Dor G, Mwanyika G, Ramphal Y, Reichmuth M, James S, Gifford R, Wilkinson E, Tshiabuila D, Preiser W, Konou A, Bitew M, Onoja B, Paganotti G, Abera A, Maror J, Kayiwa J, Abuelmaali S, Lusamaki E, , Venter M, Burt F, Baxter C, Lessells R, de Oliveira T, Tegally H

doi: 10.1101/2024.12.18.629123.
2024
Understanding the Transmission Dynamics of the Chikungunya Virus in Africa

Ramphal Y, Tegally H, San JE, Reichmuth ML, Hofstra M, Wilkinson E, Baxter C, Climade Consortium, de Oliveira T, Moir M

Pathogens
13(7):605. doi: 10.3390/pathogens13070605